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Therefore, it has been investigated in ME/CFS and a positive treatment response was reported with low dose naltrexone (LDN) (3.04.5 mg/day) in 73.9% of the patients (218 ME/CFS patients) regarding improvement in their vigilance/alertness, as well as improved physical and cognitive performance

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In a retrospective, observational, database-based study, acetyl-l-carnitine acted synergistically with pregabalin in patients with nerve compression neuropathies [49]