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Management of Vascular Dysregulation The topical alpha adrenergic receptor agonists, brimonidine and oxymetazoline, act on the smooth muscles of the superficial and deep vascular plexus and mediate vasoconstriction around the dermal vessels

Although HQ is the gold standard and the most commonly prescribed depigmenting agent for melasma management, its effects may be reversible and concerns regarding its adverse reactions including skin irritation, erythema, contact dermatitis, hypochromia, nail discoloration, and ochronosis persist 21

Waldum HL, Kleveland PM, Fossmark R

437 In addition, the MuPKS from the parrot Melopsittacus undulatus was expressed in yeast and resulted in the formation of yellow pigments known as psittacofulvins ( 220 ) that are responsible for coloration in the feathers

Ingredients: Sodium Palmate Sodium Palm Kernelate Sodium Chloride Goat Milk Powder Perfume Glycerine Titanium Dioxide Argan Oil Vitamin C Butylated Hydroxytoluene Tinogard