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We mention this not to claim GHK-Cu is "better" than retinol - it isn't a fair comparison given the difference in research depth - but because it suggests the ingredient is doing something real at the structural level when formulated and applied thoughtfully

Chronic oral toxicology studies in Han Wistar rats (6 months) and cynomolgus monkeys (9 months) found no treatment-related unscheduled deaths, toxicologically significant clinical signs, or adverse changes in organ masses, electrocardiographic parameters, or histological profiles at the concentrations examined

Over a month of weekly injections, you receive 3-5mg less total tirzepatide than planned

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