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For example, individuals with sickle cell, experience varied levels of hemolytic anemia, which reduces the oxygen-carrying capacity of the blood

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Oxidative stress, inflammation, and a decline in mitochondrial function are major contributors to this process

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As indicated above, estrogen signaling pathways play important roles in neuroprotection, as well as in the control of autophagy and ferroptosis

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Reconstitution errors

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Manifestations of glutathione synthetase deficiency usually include hemolytic anemia, often include metabolic acidosis, and sometimes include progressive neurologic symptoms as well as other systemic signs

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SLE patients receiving daratumumab usually require continued immunosuppression or maintenance therapy with belimumab to prevent the regeneration of autoreactive LLPCs (122)

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