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Two chemical processes degrade it: Hydrolysis: Water molecules attack peptide bonds, particularly at proline residues (BPC-157 contains three consecutive proline residues at positions 3, 4, and 5)

Yes, and its one almost nobody thinks of as a peptide therapy. Insulin

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The body sometimes needs a second attempt to tolerate a given dose level, and there is no penalty for taking the escalation more slowly than the standard schedule suggests