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Additionally, a study that performed bioinformatics and biochemical analyses verified this by showing that knockdown of SLC7A11 or treatment with sulfasalazine (an SLC7A11 inhibitor) exacerbated H 2 O 2 -induced ferroptosis in 661W cells (113)

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Phytother Res 20(12):11031105 [DOI] [PubMed] [Google Scholar] Panda S, Kar A (2007) Annona squamosa seed extract in the regulation of hyperthyroidism and lipid-peroxidation in mice: possible involvement of quercetin

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Finally, the authors observed that p-JNK and p-38 levels were reduced in 3-HAA-treated DC2.4 cells and bone marrow-derived DCs