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A large retrospective cohort study of 2166 patients also showed that those with HFimpEF had the lowest rates of mortality and hospitalization compared to patients with persistent HFrEF and HFpEF 8
Gallbladder Issues Research shows an increase in gallbladder-related issues in GLP-1 medication users, with conditions ranging from asymptomatic gallstones to severe cholecystitis requiring surgical intervention

Figure 3 summarises the findings from studies on the extrapancreatic effects of GLP-1-based therapies and the clinical implications of these findings

Joel Habener was a faculty member in the Endocrine Division at Massachusetts General Hospital investigating how hormones are produced

2, 3, Supplementary Fig
The finding that hypertension and higher BMI positively contribute to predicting GLP-1 M responsiveness is consistent with the current approach of using GLP-1 M for protection of the cardiovascular system and promoting weight loss [3]
