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Pediatric patients rarely require intravenous nutrient delivery unless a diagnosed condition impairs absorption or oral intake is impossible

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In addition to ARE/EpRE, AP-1 and NFB, c-Myc has been identified to also contribute to the basal expression and induction of human GCL under oxidative stress [120]

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Grx1 knockout mice show increased cellular protein S -glutathionylation 42 , and Grx2 knockout increases sensitivity to oxidative stress in mouse lens epithelial cells 43