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Studies involving patients usually need ethical approval

Methods: Peripheral blood from 23 transfusion-dependent MDS patients was analysed in a paired pre-/post-treatment design
Datopotamab deruxtecan (6-72 h) solution time-dependently induces DNA damage (via phosphorylation of H2AX , KAP1 , Chk1 ) and apoptosis (via cleavage of PARP and caspase-3) in NCI-N87 human gastric cancer cells [2]
Front Cell Dev Biol (2022) 10:982606
I.MankusD.AlarconK
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