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Under glucose-depleted conditions cells including neutrophils, glutamate undergoes glutaminolysis and form -ketoglutarate to enter the citric acid cycle and subsequently makes malate and further transform to pyruvate [28]

The shelf life while in lyophilized powder is ~24 months

Analytical conditions for optical purity: Daicel ADH column (0.46 25 cm), n-hexane (added with one thousandth of diethylamine)/ethanol = 80/20, 0.5 mL/min, = 254 nm, tR = 40.66 (R), tS = 64.22 (S)

C.GygiS