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In most animals, you would anticipate seeing some enzymes have reduced activity over time as they degrade and become less efficient, Camplisson explained

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Oncogene 25: 409418 [DOI] [PubMed] [Google Scholar] Nakamura T., Nishizawa T., Hagiya M., Seki T., Shimonishi M., Sugimura A., et al

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In this pre-targeting, the Abs-SA constructs were first delivered to localise to tumor sites, followed by the introduction of radioactive biotin, which recognizes SA