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The most common issues reported are mild irritation or sensitivity, usually related to formulation or overuse

doi:10.1016/j.nutres.2016.03.010 Dzupina A, Pella D, Zenuch P, et al

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Rather, they suggested that the above changes occurred due to alterations in post-translational modification or mitochondrial enzymes (Xu et al., 2021b)

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas