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Acknowledgments The Researchers would like to thank the Deanship of Graduate Studies and Scientific Research at Qassim University for financial support (QU-APC-2025)

doi: 10.1371/journal.pone.0002599 177 PellegattiPFalzoniSPintonPRizzutoRDi VirgilioF

However, despite many published articles using the N-to-B route to target peptides and protein to the CNS, nearly all use liquid formulations like emulsions, suspensions, and sprays, among others, and only a few use formulations in solid-state

Starting with low concentrations and limited application areas is prudent

doi: 10.3390/md17090518 148

S., Recent Advances on Bioactive Natural Products From Chinese Medicinal Plants, Medicinal Research Reviews 18, no