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"Acetyl-L-carnitine activates the peroxisome proliferator-activated receptor-gamma coactivators PGC-1/PGC-1-dependent signaling cascade of mitochondrial biogenesis." Rejuvenation Research

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MiR-33a and MiR-33b promote atherosclerosis by impairing cholesterol efflux and promoting inflammatory M1 macrophage conversion (78-80).Other microRNAs including MiR-223 and MiR-93 exhibit atheroprotective effects by increasing cholesterol efflux and conversion to the anti-inflammatory M2 macrophage phenotype (76,81-83)

Barone, R

Sequence Variations inPCSK9,Low LDL, and Protection against Coronary Heart Disease

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