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It helps keep fat in the lower body so that the like the more hip and thigh pattern instead of the abdominal fat around the organs

In a phase 2 trial (NCT02970942) of 320 individuals with biopsy-confirmed MASH, semaglutide treatment significantly increased the number of patients with resolution of MASH versus placebo 5

Low caloric intake can lead to: Low blood sugar variability Increased cortisol Reduced serotonin production All of these can show up as irritability, impatience, or emotional reactivity
