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Toyokuni S, Ito F, Yamashita K, Okazaki Y, Akatsuka S

Many studies have demonstrated that downregulation of EMT-inducing transcription factors including TWIST1 , SNAI1/SNAIL , SNAI2/SLUG , and ZEB1/2 leads to platinum sensitivity, while upregulation leads to platinum resistance (Supplementary Table S1)

Glutathione levels decline in many types of tissue as we age, and this decline can have a significant impact on brain health

Thus, ATP and ATP-mediated transporters and signaling pathways are thought to play influential roles in the development of drug resistance

Current Research & Areas of Study Early research suggests that BPC-157 may interact with biological pathways involved in cellular communication and vascular dynamics

doi: 10.21608/edj.2023.239191.2728