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Melatonin (MLT) paradoxically enhances metastatic progression in ovarian carcinoma through NE/AKT/-catenin/SLUG axis potentiation, yet concurrently attenuates chemotherapy-related sequelae (CRS)-driven oncogenesis via SLUG-mediated epithelial-mesenchymal transition (EMT) suppression in preclinical models (Sokolov et al., 2022)

For photoprotection studies, UV-irradiated controls without MT-1 pre-treatment establish baseline DNA damage levels for comparison

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Abood and Willis-Mahn say pet owners can conduct their own "at-home feeding trial" by serving a food and observing their dog

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doi: 10.1080/09712119.2007.9706642