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One of these trials is within phase 1 and aims to assess the safety of increasing doses of autologous expanded ADSCs administered via ICV injections to patients with mild to moderate AD who are less responsive to conventional treatments [60]

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Additionally, PCSK9 has been shown to raise the levels of scavenger receptors (SRs) on macrophages, including the cluster of differentiation 36 (CD36) and LOX-1

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