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In the nematode Caenorhabditis elegans, the nuclear receptor DAF-12 acts as a dietary and environmental sensor to orchestrate diverse aspects of development, metabolism, and reproduction

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The different stages of the efferocytosis process are not just a sequence of events, but a complex interplay that can interfere with the microenvironment by releasing soluble mediators (find-me signals) as a rich source of nutrients for phagocytes during the digestion process (digest-me), such as amino acids, nucleotides, lipids, and carbohydrates