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Pharmacological activation of NRF2 can mitigate the inflammation and lethality caused by DPF2 deficiency [162]

5 th ed

Other typical substrates for GSTs are pesticides, industrial intermediates, carcinogens, and environmental contaminants

The results revealed a significant reduction in the GSH contents in the kidney tissues of mice with kidney injury compared with those in normal kidney tissues, indicating a potential disruption of antioxidant defence mechanisms and ferroptosis within the kidneys

Obesity and insulin resistance are associated with endothelial dysfunction, sympathetic nervous system hyperactivity, and hyperleptinaemia, all of which can lead to hypertension

Nevertheless, they paralleled the in vitro and in vivo results regarding the antimicrobial and anti-inflammatory results