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In addition, apart from hormonal factors that affect CRP titers, such as leptin, paraneoplastic hormone production, and lower estrogenic activity in premenopausal women, low levels of vitamin A, K, and hormonal D have been associated with higher CRP levelsbut the overdose of such vitamins, especially hormonal D, can cause increased levels [1049,1050,1051]

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Significance was set at 0.05 for all comparisons