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Immunohistochemistry Substantia nigra tissues were fixed with 10% phosphate buffered formalin for 24 h, and paraffin sections were processed

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Serum antipyrine, which is metabolized by at least 10 CYP isoforms, is used to measure in vivo hepatic CYP activity

encapsulated CAY10603 (selective HDAC6 inhibitor) in PLGA nanoparticles functionalized with lactoferrin to enhance BBB permeability (lactoferrin- CAY10603-PLGA) 20

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By the way, hepatocytes and macrophages isolated from fibrotic livers displayed no alterations in COX2 , GPX4 , NCOA4 , FTL , or FTH mRNA levels compared to the control group, and there was no significant change after Ag treatment (Fig