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Lactobacillus plantarum reduces Streptococcus pyogenes virulence by modulating the IL-17, IL-23 and Toll-like receptor 2/4 expressions in human epithelial cells
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The IGFBPs that IGF-1 LR3 is designed to evade themselves have IGF-independent tumor-suppressive and pro-apoptotic roles in some tissues, so bypassing them removes another layer of physiological regulation
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