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Heavier individuals may require higher doses to achieve equivalent NNMT inhibition due to larger adipose tissue mass and potentially higher baseline NNMT activity

People taking metformin for diabetes may have reduced B12 levels and should discuss monitoring with their GP

La Belle Vie Clinic in Seattle follows a test-first, evidence-based protocol for vitamin B12 treatment aligned with NIH and AAFP clinical guidance

Common schedules include weekly injections for initial deficiency correction, then bi-weekly or monthly injections for maintenance, or as-needed for energy or performance boosts

The peptide dosing guide discusses timing considerations for various compounds

If possible take someone with you who can validate your neurological symptoms as the doctor is less likely to pooh pooh you in front of a witness