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Senescent cells upregulate FOXO4 expression to sequester p53 in the nucleus, preventing it from initiating the mitochondrial apoptosis pathway
Understanding these mechanisms could inform new strategies to prevent metastasis and improve patient outcomes (120)
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This is similar to values previously reported for the release of GSH from cultured astrocytes [88, 89]
A.UmarS.AhmadA.IqbalM.KhanN
E.YamoriW.EvansJ
