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A progressive decrease in GPx1 expression has been observed in pancreatic cells transitioning from a healthy pancreas to chronic pancreatitis and ultimately to pancreatic cancer (Cullen et al

10.1097/FJC.0000000000000852 J

High-grade prostatic intraepithelial neoplasia

(2024) 6:e751e61
Jager RD, Mieler WF, Miller JW

The key in production is ensuring that the final product is in the reduced form (GSH) rather than the oxidized form (GSSG)
