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Activation of SSAT1/ALOX15 axis aggravates cerebral ischemia/reperfusion injury via triggering neuronal ferroptosis

Translating these findings into human applications could unlock new treatments for insomnia and stress-related sleep disturbances

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Illustration of a typical affinity purification

In the long-term toxicity experiment, continuous injection of AOD 9604 (10 mg/kg) for 8 weeks did not cause abnormal liver and kidney functions or fluctuations in blood glucose, providing a safety basis for its further research and application

Care Med 2024, 209, 427443