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as well as in the normal function of the brain and the nervous system

Sudan IV staining was performed after 30 minutes of differentiation in 70% alcohol, followed by washing with running water for 1 hour 47 The area of the atherosclerotic lesion (Sudanophilic area) was measured using image analysis software to calculate the proportion of plaque to the area of the entire aorta (WinROOF 6.5, Mitani, Tokyo)

In the network, the nodes represent enzymes and activator metabolites, and the edges are formed between nodes when an enzyme is activated by a metabolite (Fig

P i (upper case) is the macro partition coefficient, where subscript i refers to the ionization state of species included in P i

The formation of these inactive aggregates represents a major bottleneck, influenced by factors ranging from cultivation conditions (e.g., temperature, pH, ionic strength) to intrinsic properties of the target protein itself, such as a high proportion of hydrophobic residues, the presence of intrinsically disordered regions, complex multidomain architectures, or the requirement for specific eukaryotic chaperones or post-translational modifications absent in the prokaryotic host [2, 3]

Dev Dyn 201:227235
