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Additional, supplementation of sodium pyruvate and JX06 in GGCT-knockdown cells confirmed that this regulatory effect of GGCT-mediated changes in ROS was independent of energy metabolism pathways

At this stage, it is worth exercising extreme caution - rather, the peptide should be allowed to dissolve in water on its own, and certainly should not be shaken vigorously

10.1007/s00401-018-1835-x Acta Neuropathol

However, other studies (e.g., JCAD Online 2019) reported variable results and advised caution with unregulated supplements

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