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Total number of axons, axon fiber size, myelin thickness, G-ratio, axon number/mm 2 , diameter of fiber, changes of longitudinal width, and formation of the edema and hematoma were evaluated by transmission electron microscopy

Results Using 53 search terms related to digital health and the ten selected rare diseases (see Supplementary Table 1), a total of 8373 clinical trial records and publications were initially retrieved from Clinicaltrials.gov, the ICTRP, Cochrane, PubMed and Web of Science

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