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B12 plays a key role in several processes like producing red blood cells, converting food into energy, and producing nerves

Recommended B12 intake is dependent on the level of your deficiency

Patients who typically benefit from vitamin B12 injections include individuals diagnosed with vitamin B12 deficiency, those experiencing difficulties absorbing nutrients through their digestive tract, or patients who follow restrictive dietary patterns, such as strict vegetarians or vegans

However, ScMCP- 1 negatively correlated with serum HDL (Additional file 1: Table 5)

Crohn's Disease and Celiac Disease: Both of these inflammatory conditions can damage the terminal ileumthe very last section of the small intestine where B12 absorption happens

Olasupo Odunsi, MD, Medical Director Reviewed July 5, 2026 If you're constantly tired and your metabolism feels stuck, low B12 could be part of the problem