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Of the 1,283 screened individuals, 223 men and women were enrolled, ranging in age from 18 to 85 years

CAT, catalase

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In summary, the acetyl-L-carnitine group scored better when assessing patient function using the modified Rankin Scale (mRS) and National Institutes of Health Stroke Scale (NIHSS) score, and supplementation caused a significant decline in the serum levels of TNF- , ICAM-1, IL-6, and NSE and a significant increase in the serum level of superoxide dismutase (SOD), TAC, GPx, and total L-carnitine in the subjects with acute ischemic stroke compared to the placebo treatment

Covariate collection Trained nurses meticulously gathered all covariate data during the enrolment process