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P., Keck, T., Auer, G., and Habermann, J

CXCR6 marks a novel subset of T-bet(lo)Eomes(hi) natural killer cells residing in human liver

Graphical Abstract Similar content being viewed by others Background Ferroptosis, a regulated type of cell death resulting from iron-dependent lipid peroxidation, has been recognized as a crucial mechanism associated with the development of various diseases, including neurodegenerative, cardiovascular, digestive, musculoskeletal, and cancer-related diseases [1]

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This was an unanticipated finding since TMAO is associated with cardiovascular and metabolic disease and AD and prior human studies showed modulation of plasma TMAO by the E4 allele (Fennema et al., 2016