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[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Smitherman P.K., Townsend A.J., Kute T.E., Morrow C.S

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Pain, arising from the underlying disease process, surgical trauma, or wound care procedures, can also indicate healing disturbances, infection, or inadequate wound management [28,29]

Younger individuals typically respond faster, though older users still report benefits

Consistent with this, use of a reducing source such as -mercaptoethanol allows reversal of xCT-KO phenotype, as it has been reported couple decades ago by Bannai's group ( in vivo can explain the discrepancy with in vitro phenotype

As a result, it has broader reach than antioxidants that only act in one location