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What Is AOD 9604
J., Simpson K., Hume D

Heart failure or significant cardiac conditions: IV fluid volume can increase cardiac workload
It is crucial to distinguish that the central energy deficit specifically refers to metabolic dysfunction within the central nervous system, impacting both neurons and glial cells (such as impaired glucose metabolism and mitochondrial dysfunction), rather than a deficiency in cerebral perfusion due to circulatory system dysfunction

Antioxid Redox Signal 2025;42:62339

This conclusion is also based on a large number of clinical studies relating lower levels of serum UA to increases in PD prevalence or progression