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So if either of these denaturing agents are required for your purification, youll want to carefully optimize the concentration that you need, or consider using a different type of affinity tag

Further mechanism studies reveal that the loss of SLC27A5 enhances the glutathione reductase (GSR) expression in a nuclear factor erythroid 2-related factor 2 (NRF2)-dependent manner, which maintains glutathione (GSH) homeostasis and renders insensitive to sorafenib-induced ferroptosis

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