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Mechanisms and epidemiology Nociplastic pain stems from central sensitization, involving abnormal pain processing in the peripheral and central nervous systems, leading to increased sensitivity and reduced inhibition

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Regulation of cholesterol 7-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXR)

In contrast, however, we noticed an overall increase in the size of dispersed microcolonies of PDH treated biofilms (Fig