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Furthermore, high antioxidant activity of bioactive peptides is generally indicated by a molecular weight less than 10 KDa 41

[DOI] [PMC free article] [PubMed] [Google Scholar] [164].Zheng J, Sato M, Mishima E, et al

MOTS-C activates AMPK pathways to improve insulin sensitivity, mitochondrial function, and metabolic flexibility

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The water-soluble -glucuronide linker is stable in plasma, effectively delivers drugs to target cells and allows for potent activities comparable to that of a free cytotoxic drug [79]
