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in some type of cancers, CAT activity was lower in patients, especially in lymphomas, when compared with CAT activity in the normal population [62] and, in bipolar disorder, subjects with bipolar depression presented a significant increase in CAT levels [63]

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PET tracers showed that cancer cells rely heavily on glutamine uptake via mTORC1 signaling, while myeloid cells in the TME are more dependent on glucose, as are T cells and cancer cells (but to a lesser extent) 128

Effects of increased intraocular pressure on rat retinal ganglion cells

Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis