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There are three major catabolic routes that produce 2-ketoadipic acid
This process is vital for the health of high-energy tissues like the heart and skeletal muscles
It has been proposed that CPT1A contributes to cell survival, not only by increasing FAO 29 but also by stimulating histone acetylase activity in the nucleus 30

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Structural MRI outcomes and predictors of disease progression in amyotrophic lateral sclerosis
