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The tumor selectivity of our prodrug was determined by comparing platinum organ/tumor ratios (Fig

HIF-1 stabilization leads to metabolic reprogramming (e.g., a shift towards glycolysis) that can indirectly affect mitochondrial ROS production [64]

There were two blocks, each one including 192 trials (64 for each condition: shape, color or number)

therefore, the treatment is elective

Engelen M, van Ballegoij WJC, Mallack EJ, et al