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However, intranasal delivery of curcumin has shown to enhance its brain uptake efficiency in a rodent model of oxidative damage in cortical neurons[141]

Limitations include reliance on animal models (e.g., germ-free mice) that do not fully mimic human physiology, small human cohorts, and variable sequencing methods leading to non-reproducible taxa changes

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, Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice

Previous studies suggest that there is a significant relationship between male infertility and a multitude of factors, including hormonal imbalances, genetic abnormalities, varicocele, infections, age, obesity, smoking, alcohol consumption, environmental toxins, and exposure to heat or radiation [16, 17]

Novel action of paclitaxel against cancer cells: Bystander effect mediated by reactive oxygen species