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Inhibitory effect of celastrol on adipogenic differentiation of human adipose-derived stem cells

is a state of unbalanced tissue oxidation refers to a condition in which cells are subjected to excessive levels of molecular oxygen or its chemical derivatives called reactive oxygen species (ROS).Under physiological conditions, the molecular oxygen undergoes a series of reactions that ultimately lead to the generation of superoxide anion (O 2 -), hydrogen peroxide (H 2 O 2 ) and H 2 O