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Description
The multifaceted nature of PD comorbidities necessitates a precision medicine approach tailored to the patients full clinical context ( 4.1 Neuropsychiatric symptoms: depression, anxiety, and cognitive decline Over 4060% of PD patients experience depression and anxiety, which are often underdiagnosed and misattributed to motor disability ( Cognitive impairment, ranging from mild cognitive dysfunction to Parkinsons disease dementia (PDD), affects up to 80% of individuals in advanced stages (25)

Sorafenib can also be used in combination with various chemotherapy drugs, including paclitaxel, cisplatin, and 5- fluorouracil

Similarly, the mouse model where -catenin was selectively deleted in Wnt-responsive cells in the dorsal part of the otocyst shortly before canal pouch evagination displayed the failure of formation of two of the SSCs

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After irradiation, resveratrol showed peaks at 306 nm (trans-resveratrol) and 287 nm (cis-resveratrol)

During liver development, Wnt signaling promotes the proliferation, expansion, and differentiation of HPCs (Perugorria et al., 2019)
