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These guidelines help ensure that the medication is prescribed to individuals who are most likely to benefit from its weight-reducing effects

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63 Considering that T2DM and MASLD can reciprocally cause and affect each other, and given liraglutides potential therapeutic characteristics for MASLD, which may be beneficial for anti-fibrosis, more aggressive use of higher doses may bring greater clinical benefits in some groups, such as those with higher-grade fibrosis with or without T2DM

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in a 5-year longitudinal cohort study found a stronger association, reporting that semaglutide exposure more than doubled the risk of NAION (91)

These systems accumulate in ischemic brain regions, scavenge ROS, deliver oxygen, and significantly reduce infarct size in middle cerebral artery occlusion (MCAO) models [307]