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Collectively, data show that elevated plasma TMAO levels contribute to inflammatory and cardio-metabolic risks via the induction of inflammatory cytokines [72,73]

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In addition, cisplatin destroys normal hematopoiesis by reducing the production of colony-forming unit granulocytes/macrophages (CFU-GM) [60, 61]

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Plasma extracellular vesicle proteomic profiling showed unique protein changes in immune-related pathways and T cell functions

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