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For example, iron generates hydroxyl radicals via the Haber-Weiss reaction and the Fenton reaction, which promote ROS formation, and acute myeloid leukemia (AML) cells induce ferroptosis in AML cells by increasing ROS levels via the HMGB1-regulated RAS-JNK/p38 signaling pathway [149]

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The theoretical pathway exists, but clinical human studies have produced mixed results

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Philadelphia Spine Research Symposium PSRS, Philadelphia, Pa 11/2 Are HRQOL Outcomes Of ACDF Influenced By Smoking Status

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However, mechanistic data on TEC-driven platinum resistance in ovarian cancer remain scarce

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[PubMed] [Google Scholar] 71.Thomson C., Paterson E

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