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Both compounds can be metabolized to oxidation products and conjugated with glutathione

They are not recognized as generally regarded as safe (GRAS) substances for dietary supplement use

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In this method, hot water (~78 C) was used to disrupt the yeast cells, releasing intracellular glutathione along with other water-soluble components, following which the suspension was rapidly cooled using ice and centrifuged at room temperature for 20 min