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Description
Dermal fibroblasts have a substantial role in constructing the ECM of the skin, which contains two major classes of biomolecules

Complete rest leads to deconditioning and does little to stimulate active repair

It stimulates glycosaminoglycan synthesis the production of hyaluronic acid and dermatan sulfate that hydrate skin and provide the scaffolding for collagen deposition

That mechanism research underpins the rationale for systemic GHK-Cu dosage protocols

Health goals + history + baseline needs

Adenosyl B12, the other active form, showed a much lower effect
