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A 20 percent LDL reduction from a weight-loss-oriented triple agonist is therefore a genuinely new observation and helps explain why retatrutide is being developed across cardiovascular, metabolic, and weight-related indications rather than as a pure obesity asset

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Full disclosure: Inform your healthcare provider about any existing medical conditions, especially diabetes, thyroid issues, or a family history of medullary thyroid cancer or multiple endocrine neoplasia type 2

doi: 10.1590/S1678-77572011000300002